What is Yunnan Baiyao? Authentic Yunnan Kunming specialty: Yunnan Baiyao
Content summary:Do you want to know what Yunnan Baiyao is? This article is a detailed introduction to Yunnan Kunming specialty - Yunnan Baiyao. It was compiled and edited by the editorial team of China Specialty Network after reviewing and collecting relevant information about Yunnan Baiyao. The full text takes about 8 minutes to read, mainly including the basic introduction of Yunnan Baiyao and the product characteristics of Yunnan Baiyao? How did the history of Yunnan Baiyao come about? The production method of Yunnan Baiyao and the awards and honors of Yunnan Baiyao
Basic Introduction to Yunnan Baiyao
Yunnan Baiyao is a traditional Chinese medicine. In 1979, 1984, and 1989, it was awarded the National Gold Medal for High Quality Products three times. The products include traditional bottled and capsule formulations. Known as the holy medicine for healing wounds, the "Wan Ying Bai Bao Dan", later known as Yunnan Baiyao. With a history of over a hundred years, prescriptions are a secret in the field of economic intellectual property rights of the Chinese government 1. Hemostasis: Yunnan Baiyao can significantly shorten the clotting time of rabbits and humans, shorten the prothrombin time of rabbits, shorten the bleeding time of rats, and counteract the anticoagulant effects of heparin and coumarin. Its coagulation mechanism is produced by increasing the permeability of platelet membrane, causing the release of platelet components, including adenosine monophosphate and calcium, similar to the platelet response induced by thrombin. Its hemostatic effect mainly comes from the active ingredients in the drug, independent of its pH and vascular constriction<2. Promoting blood circulation and removing blood stasis: Yunnan Baiyao can significantly improve microvascular circulation disorders caused by high molecular weight glucosides, significantly reduce thrombosis caused by ligation in the inferior vena cava of rats, and reduce thrombus weight. Compared with the control group, there is a significant difference. (P< 0.01) 3. Anti inflammation: Subcutaneous injection of Yunnan Baiyao total saponins has inhibitory effects on the primary lesions of adjuvant polyarthritis in rats, paw swelling caused by carrageenan, leukocyte chemotactic inflammation model, and swelling caused by cotton ball granulation tissue. Its anti-inflammatory mechanism can be achieved by inhibiting the release of inflammatory mediators histamine and prostaglandin E, and combating joint swelling and increased capillary permeability caused by both. On the other hand, it can promote the secretion of corticosteroids<4. Increase myocardial nutritional blood volume: Using isotope 8bRB to measure myocardial nutritional blood flow in mice, it was found that Yunnan Baiyao can significantly increase myocardial nutritional blood flow, with the strongest effect observed within 30 minutes 5. Increase immune function of the body: Using radioactive colloid assay, Yunnan Baiyao can significantly increase the radioactivity in mouse liver glands, that is, increase liver and spleen phagocytic function 6. Anti cancer: Two saponins I and VI isolated from Yunnan Baiyao showed certain anti-cancer activity in P-388, L-1210, and 9KB tissue culture system screening experiments< 7. Yuchuang: It can significantly promote the expression of basic fibroblast growth factor (bEGF) and vascular endothelial growth factor (VEGF) in the body, thereby accelerating vascular growth and promoting wound healing The formula and production method of Yunnan Baiyao are never disclosed. In 1955, Miao Lanying presented the formula to the Central People's Government of the People's Republic of China, and it has been kept confidential by the Ministry of Health of the People's Republic of China ever since. Afterwards, some books and magazines published information about the formula and preparation method of Yunnan Baiyao, but the producers claimed that "none of them are correct". The research and identification of the original plant of Yunnan Baiyao, as well as the isolation and structural identification of its chemical components, have always attracted the attention of scientists from various countries and have been analyzed using various modern analytical methods. Analysis using an emission spectrometer revealed the presence of calcium and phosphorus elements in Yunnan Baiyao. When analyzed by spectroscopy, no UV absorption was observed; The infrared absorption spectrum shows a spectrum similar to that of kudzu starch, which can be inferred to be the same substance. After analyzing with thin-layer chromatography, the same conclusion was also obtained, indicating that Yunnan Baiyao may have used kudzu starch as an excipient. Supercritical fluid chromatography was used to determine the presence of substances such as panaxadiol and panaxatriol in Yunnan BaiyaoThe production method of Yunnan Baiyao